Renin angiotensin blockers and cardiac protection: from basics to clinical trials

BI Lévy, JJ Mourad - American Journal of Hypertension, 2022 - academic.oup.com
… for patients who have presented intolerance to ACE inhibitors. … of telmisartan as first-line
treatment in high-risk patients. … The effect of the AT1R on cardiac remodeling is well established, …

[HTML][HTML] Glucose and blood pressure-dependent pathways–the progression of diabetic kidney disease

DM Patel, M Bose, ME Cooper - International journal of molecular …, 2020 - mdpi.com
… In this review, we will primarily focus on diabetic nephropathy. … patients with albuminuria, a
similar effect on albuminuria and GFR decline was observed with telmisartan and enalapril [74…

From ACE inhibitors/ARBs to ARNIs in coronary artery disease and heart failure (part 2/5)

DP Leong, JJV McMurray, PG Joseph… - Journal of the American …, 2019 - jacc.org
… and telmisartan did not reduce the primary outcome event … to ACE inhibitor versus a control
arm that measured renal disease … with diabetic nephropathy (mean baseline serum creatinine …

Blockade of renin angiotensin system ameliorates the cardiac arrhythmias and sympathetic neural remodeling in hearts of type 2 DM rat model

YM Yehya, AM Hussein, K Ezam, EA Eid… - … & Immune Disorders …, 2020 - ingentaconnect.com
… at the level of either ACE by enalapril or angiotensin (Ag) receptors … , and cardiac remodeling
in the absence of coronary arteryEffects of telmisartan compared with eprosartan on blood …

[PDF][PDF] Possible renoprotective effect of valsartan/sacubitril versus valsartan and Metformin in rat model of diabetic nephropathy

DI Tawfik, DM Elkhashab, RK Abou Elnour… - Journal of Advanced …, 2023 - japer.in
… End-Stage Renal Disease is also a result of diabetic nephropathy. The first-line therapy for
patients with diabetesEffect of sacubitril/valsartan versus enalapril on glycaemic control in …

[HTML][HTML] Therapeutic insights in chronic kidney disease progression

A Shabaka, C Cases-Corona… - Frontiers in …, 2021 - frontiersin.org
… its effect on cardiovascular risk and end-stage kidney disease… The benefit from ACE inhibitors
in terms of reaching ESKD or … in diabetic nephropathy, hypertensive kidney disease, and …

Multimodal efforts to slow the progression of chronic kidney disease in patients with type 2 diabetes mellitus

A Rastogi, MR Weir - Journal of Diabetes and its Complications, 2023 - Elsevier
… and ARBs for their kidney and CV protective effects when used … telmisartan in patients with
vascular disease or high-risk … both hypertensive vascular disease and diabetic nephropathy. …

Simultaneous inhibition of neprilysin and activation of ACE2 prevented diabetic cardiomyopathy

V Malek, N Sharma, AB Gaikwad - Pharmacological Reports, 2019 - Elsevier
… combination therapy against diabetic nephropathy. However, this … ) or ACE inhibitor (ACEi))
against cardiovascular diseases (… such combination of telmisartan and thiorphan prevented …

Hypertension and cardiovascular disease in patients with chronic kidney disease

SM Hamrahian - Approaches to Chronic Kidney Disease: A Guide for …, 2022 - Springer
heart failure (CHF), stroke, peripheral vascular disease (PVD)… A high-salt diet blunts the effect
of ACE inhibitors, whereas … bilateral renal artery stenosis that requires further investigation. …

Angiotensin type 1 receptor blockers in heart failure

KD Singh, SS Karnik - Current drug targets, 2020 - ingentaconnect.com
… antiinflammatory effects in patients with diabetic nephropathy [… Effect of telmisartan and
enalapril on ventricular remodeling and kidney prognosis of patients with coronary artery disease